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Tumor

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M2-PK:

a target of different oncoproteins (oncogenes)

Pyruvate kinase type M2 (M2-PK, PKM2) is a target of different oncoproteins with totally different physiological functions:

M2-PK : a target of the pp60v-src kinase

M2-PK: a target of the HPV-16 E7 oncoprotein

M2-PK: a target of HERC1

M2-PK: a target of the A-Raf kinase

 

Pyruvate Kinase isoenzymes : M2-PK
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