Comparison of sensitivities of Tumor M2-PK, CEA, CA19-9 and CA 72.4 in pancreatic tumors

nm = non metastasized; m = metastasized; t = total
n.d.a. = no data available

Sensitivities for combination of Tumor M2-PK with classical tumor markers

Schulze, 2000:    Tumor M2-PK + Ca 19-9:           96 %

Ventrucci et al., 2001:    Tumor M2-PK + CA 19-9:     96 %

Tumor M2-PK concentrations were measured with a sandwich ELISA from ScheBo Biotech AG, Giessen, Germany.

CEA, CA-19-9 and CA 72-4 were determined using, Cobras Core II from Roche Diagnostics, Mannheim, enzymun Test-ES 600 Immunology Multianalyzer as well as tests from Sorin Diagnostics, Saluggia.

References

Tumor M2-PK: clinical relevance for metabolic profiling of tumors

Metabolic tools for tumor diagnosis

Pyruvate kinase isoenzymes: M2-PK