Glycolysis: a pool of precursors for synthetic processes

The intermediates of glycolysis, such as glucose 6-phosphate, fructose 6-P, glyceraldehyde 3-P, dihydroxyacetone-P, glycerate 3-P can be used as precursors for the synthesis of cell building material, such as nucleotides, amino acids, phospholipids and triglycerides. 

Metabolic scheme

In proliferating cells the tetramer:dimer ratio of M2-PK determines whether the glucose carbons are degraded to lactate under the production of energy or channelled into synthetic processes.