Tumor M2-PK: Correlations in melanoma

Vmax activities of pyruvate kinase
in homogenates
of healthy skin and melanoma

PK_activity02

Vmax activities were measured spectrophotometrically according to the following reaction:

Pyruvate02

Tumor M2-PK concentrations
in homogenates
of healthy skin and melanoma

Tumor_M2-PK02

In melanoma tissues pyruvate kinase activities as well as the amount of Tumor M2-PK (dimeric form) increase.

Tumor M2-PK concentrations
in EDTA plasma samples
from patients with melanoma

Tumor_M2-PK_U_M02

Tumor M2-PK measurements in EDTA-plasma samples: Selma Ugurel

 

Combination of Tumor M2-PK with S100-beta

 

References

Tumor M2-PK: clinical relevance for metabolic profiling of tumors

Metabolic tools for tumor diagnosis

Pyruvate kinase isoenzymes: M2-PK